Jose Mourinho has made four changes to his Manchester United side – and the headline is that Wayne Rooney misses out.
Also out are the banned Zlatan Ibrahimovic, Ashley Young and Marouane Fellaini.
In come Antonio Valencia, Ander Herrera, Anthony Martial and Marcus Rashford.
Man Utd: de Gea, Valencia, Jones, Rojo, Darmian, Carrick, Ander Herrera, Mata, Pogba, Martial, Rashford. Subs: Depay, Rooney, Lingard, Blind, Young, Romero, Schneiderlin.
There are three changes for Arsenal. After some speculation it’s confirmed that Alexis Sanchez does start.
In come Carl Jenkinson, Mohamed Elneny and Aaron Ramsey for Hector Bellerin, Granit Xhaka and Alex Iwobi.
Arsenal: Cech, Jenkinson, Mustafi, Koscielny, Monreal, Coquelin, Elneny, Walcott, Ozil, Ramsey, Sanchez. Subs: Gibbs, Gabriel, Giroud, Ospina, Oxlade-Chamberlain, Iwobi, Xhaka.